hrp0089p3-p416 | Diabetes & Insulin P3 | ESPE2018

A Rare and Unexpected Cause of Diabetes in Childhood

Makaya Taffy , Basu Supriyo , Ali Aishatu

Background: Pancreatogenic diabetes is rare in children. The prevalence is 5–10% of all cases of diabetes in the developed world. The underlying pathophysiology is destruction of islet cells by pancreatic inflammation.Case: A 15-year old previously healthy boy presented with polyuria, polydipsia, abdominal pain and loss of weight (LOW) over several weeks. Family history revealed a three-generational history of diabetes including reported type-1 (T1D...

hrp0082p2-d2-334 | Diabetes (1) | ESPE2014

New-Onset Type 2 Diabetes Presenting with Hyperglycaemic Hyperosmolar State in a Renal Transplant Patient on GH Treatment

Harrington Francesca , Makaya Taffy , Wolfenden Helen

Background: Hyperglycaemic hyperosmolar state (HHS) is a life-threatening condition rarely seen in paediatrics. It is however becoming increasingly recognised with the growing incidence of childhood type 2 diabetes mellitus (T2DM).Objective and hypotheses: We present a child with Bardet–Biedel syndrome (BBS), with new-onset T2DM presenting in HHS, and discuss the dilemmas encountered in his management due to multiple co-morbidities, including renal ...

hrp0092p3-299 | Late Breaking Abstracts | ESPE2019

Review of Neonatal Cortisol Evaluation between 2012–2018 in a Single Centre: Trends, Outcomes and Associations

Makaya Taffy , Sarvasiddhi Satish , Menon Smrithi , van Boxel Elizabeth-Jane , Shine Brian

Background: Neonatal cortisol assessment is indicated in suspected adrenal insufficiency. Clinical presentation includes: low blood glucose, low blood pressure, ambiguous genitalia, electrolyte abnormalities, midline abnormalities.Aims: Review the trends, outcomes and associations of cortisol assessment in neonates within our Trust between 2012-2018.Objectives: Review:<p class=...