ESPE Abstracts

Background: ROHHAD/ROHHADNET syndrome (rapid-onset obesity with hypothalamic dysfunction, central hypoventilation, autonomic dysregulation with or without neural tumor - NET) – has been reported in association with cerebral venous thrombosis events, as reported also in central hypoventilation syndrome. It is not clear whether thrombotic risk represents a cause or a consequence of hypoventilation and hypothalamic dysfunction. Aim of our study was to chara...

Introduction: Central diabetes insipidus (CDI) diagnosis is challenging, since water deprivation test has sub-optimal sensitivity and specificity and carries an important burden for patients and care-givers. Several authors have investigated arginine as a stimulus for AVP secretion – evaluated by dosing copeptin, a pre-pro AVP cleavage product - and normal values for adult patients have already been established.Aims and Met...