hrp0092p2-210 | Multisystem Endocrine Disorders | ESPE2019

Autoimmune Thyroiditis and Autoimmune Hepatitis Presenting at Onset of Type 1 Diabetes (T1D)

Marchant Alice , Chizo Agwu Juliana

Background: Autoimmune disease (AD) occurs due to loss of immunological tolerance to self-antigens and can be organ specific or systemic. One in four patients with a single AD may develop another AD. The presence of three or more AD is described as multiple autoimmune syndrome (MAS) in which Type 3 subset includes autoimmune thyroiditis and T1D, but not autoimmune hepatitis. Type 2 Autoimmune Polyendocrine Syndrome can be diagnosed when T1D and autoimmune thyr...