hrp0098p1-227 | Diabetes and Insulin 4 | ESPE2024

Higher levels of c-peptide at the onset of Type 1 Diabetes are correlated with better glycemic control after 2 years from the diagnosis in a cohort of pediatric patients.

Marigliano Marco , Piona Claudia , Mancioppi Valentina , Morotti Elisa , Fornari Elena , Olivieri Francesca , Morandi Anita , Maffeis Claudio

Background and Objective: Diabetic ketoacidosis (DKA) is an acute endocrinological emergency in childhood. It occurs in 20-40% of cases at the onset of Type 1 Diabetes (T1D). DKA is classified as mild, moderate, and severe based on the clinical picture and blood pH levels. This study aims to evaluate the relationship between the characteristics of T1D onset (DKA level, pH, c-peptide) and the glycometabolic control 2, 5, and 10 years after the diagnosis.<p ...

hrp0098p1-228 | Diabetes and Insulin 4 | ESPE2024

The use of pumps with Automated Insulin Delivery (HCL/AHCL) improves the Sleep Quality of Children and Adolescents with Type 1 Diabetes and of their parents/caregivers.

Marigliano Marco , Piona Claudia , Mancioppi Valentina , Morotti Elisa , Fornari Elena , Olivieri Francesca , Morandi Anita , Maffeis Claudio

Background and Objective: Type 1 Diabetes (T1D) is one of the most frequent endocrine-metabolic diseases in children and youth. Several studies assessed Sleep Quality (SQ) in Children with Diabetes (CwD), yielding conflicting results. This study aims to test the hypothesis that the use of glucose sensors and insulin pumps in T1D is associated with better QOL and SQ in a group of CwD and their parents/caregiversSubjects and Method...

hrp0098rfc1.6 | Diabetes and Insulin | ESPE2024

Metabolic dysfunction-associated steatotic liver disease and its association with glycemic control metrics in children and adolescents with type 1 diabetes: an exploratory study

Maffeis Claudio , Piona Claudia , Morandi Anita , Marigliano Marco , Morotti Elisa , Mancioppi Valentina , Zusi Chiara , Emiliani Federica , Mantovani Alessandro , Colecchia Antonio , Targher Giovanni

Context: Metabolic dysfunction-associated fatty liver disease (MASLD) is the most common chronic liver disease. Recent data showed that MASLD is a common condition also in adults with type 1 diabetes (T1D) and it is independently associated with an increased risk of diabetic complications.Aims: To examine the prevalence of MASLD and its association with glycemic control metrics in children and adolescents with T1D.<p...

hrp0084p1-32 | Diabetes | ESPE2015

Aetiological Diagnosis of Diabetes in Italian Diabetic Children and Adolescents

Delvecchio Maurizio , Salzano Giuseppina , Mozzillo Enza , Frontino Giulio , Patera Ippolita Patrizia , Toni Sonia , Rabbone Ivana , Cherubini Valentino , Tumini Stefano , D'Annunzio Giuseppe , Iughetti Lorenzo , Maltoni Giulio , Cauvin Vittoria , Marigliano Marco , Barbetti Fabrizio

Background: Type 1 diabetes (T1D) is the most frequent etiology in Italian diabetic children and adolescents. Data on type 2 (T2D) and monogenic diabetes (MD) prevalence are scanty.Objective and hypotheses: To estimate the prevalence of T1D, T2D, secondary diabetes, and MD in a pediatric population of Italian diabetic patients.Method: Data on 3,076 patients (diabetes onset January 2007–December 2012, age at diagnosis <18 y...