hrp0086p1-p482 | Fat Metabolism and Obesity P1 | ESPE2016

Changes in Urine and Plasma Metabolomics Profiles after a Lifestyle Intervention Program in Obese Prepubertal Children

Jesus Leal Witt Maria , Llobet Marina , Samino Sara , Rodriguez Miguel A. , Yanes Oscar , Ramon Marta , Lerin Carles

Background: Obesity is one of the major risk factor for metabolic and cardiovascular disorders, and its global prevalence has increased exponentially in the last decades. Excessive weight gained during early childhood increases long-term risk; however, reversing this condition during early-life reduces risk, improving childrenÂ’s quality of life.Objective and hypotheses: We hypothesized that a lifestyle intervention in obese prepubertal children woul...

hrp0084p2-383 | Fat | ESPE2015

Tryptophan Supplementation as Conjunctive Therapy to Life Style Changes in Obese Adolescents

Jaramillo Adriana , Calderon Caterina , Llobet Marina , Sole Laura , Suarez-Ortega Larisa , Lerin Carles , Ramon-Krauel Marta

Background: The correlation between obesity and depression is well established. Tryptophan (Trp) is an essential amino acid that acts as substrate for serotonin and melatonin biosynthesis, both know to play a role in satiety, anxiety, and depression. Furthermore, low plasma Trp levels have been associated with obesity.Objective: To investigate the effects of Trp supplementation as a conjunctive therapy to conventional life-style intervention on weight lo...