hrp0098p1-89 | Sex Endocrinology and Gonads 1 | ESPE2024

Organokines and liver enzymes in adolescent girls with polycystic ovary syndrome during randomized treatments

Garcia-Beltran Cristina , Peyrou Marion , Navarro-Gascon Artur , López-Bermejo Abel , de Zegher Francis , Villarroya Francesc , Ibáñez Lourdes

Introduction: Polycystic ovary syndrome (PCOS) is often related to metabolic associated fatty liver disease (MAFLD). MAFLD has been associated with altered hepatic function and systemic dysmetabolism and with abnormal circulating levels of signaling molecules, so-called organokines. Here, we assessed the effects of two randomized treatments on a set of organokines in adolescent girls with PCOS and without obesity, and report the associations with circulating b...