hrp0098fc4.2 | Adrenals and HPA Axis 1 | ESPE2024
Idkowiak Jan
, Melau Cecilie
, E Taylow Angela
, Juul Anders
, T Mitchell Rod
, Arlt Wiebke
, Jørgensen Anne
Background: Previous descriptions of the steroidogenic capacity of human foetal adrenal glands in an ex vivo culture system focused on the classic androgen pathway and the alternative DHT pathway. However, no information is available on the abundance and role of the adrenal-derived 11-oxygenated androgens during foetal development, and how their levels correlate to classic androgens.Aim: To characterise the ster...