hrp0098p1-142 | Fat, Metabolism and Obesity 3 | ESPE2024

The effect of a personalized, lifestyle intervention program on SFRP5 concentrations in children and adolescents with obesity

Koutaki Diamanto , Paltoglou George , Michos Athanasios , Bacopoulou Flora , Charmandari Evangelia

Background: Secreted frizzled-related protein 5 (Sfrp5) is a relatively novel adipokine with anti-inflammatory properties. Recent evidence suggests that it plays a role in obesity and its metabolic complications. However, data on Sfrp5 regulation in relation to obesity in children are scarce.Objective: To investigate the effect of a 1-year personalized, comprehensive, multi-disciplinary, lifestyle intervention program of...