hrp0098p1-267 | Growth and Syndromes 4 | ESPE2024

The clinical burden and healthcare resource utilization among children and adolescents with achondroplasia: an observational cohort study using Optum’s de-identified Clinformatics® Data Mart Database

Abraham Pranav , Miles Gandarvaka , Petruski-Ivleva Natalia , I. Berger Kenneth

Background: Achondroplasia is the most common skeletal dysplasia associated with inhibited growth development and disproportionately short stature; morbidity and complications are apparent at birth and continue throughout life. We assessed the clinical and healthcare resource utilization (HCRU) burden of achondroplasia in US children and adolescents.Methods: This retrospective study assessed children and adolescents (age...

hrp0098p2-54 | Bone, Growth Plate and Mineral Metabolism | ESPE2024

The clinical burden and healthcare resource utilization among children and adolescents with osteogenesis imperfecta: an observational study using Optum’s de-identified Clinformatics® Data Mart Database

Abraham Pranav , Miles Gandarvaka , Petruski-Ivleva Natalia , Hawaldar Kalyani , I. Berger Kenneth

Objectives: Osteogenesis imperfecta (OI) is a skeletal dysplasia affecting 1–2 individuals per 20,000 live births, but the burden of disease in children and adolescents remains unclear. We assessed the clinical and healthcare resource utilization (HCRU) burden of OI in US clinical practice.Methods: This retrospective cohort study included children and adolescents (aged ≤19 years) with OI (≥1 inpatient claim, ...