hrp0089p1-p244 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P1 | ESPE2018

Polycystic Ovarian Syndrome in Adolescents: Characterising the Clinical Phenotype and the Role of Precision Medicine

Gunn Harriet , Agarwalla Vathsala , Skinner Rachel , Milne Bronwyn , Mills Kevin , Steinbeck Katharine

Background: Polycystic ovarian syndrome (PCOS) is the most common hormone disorder in adolescent and young adult females, affecting 4–20% of the population. PCOS is associated with metabolic dysfunction, pro-inflammatory processes and mood disorders. Despite this, it is poorly understood in younger adolescents, and diagnosis and management remain challenging.Objectives: To better understand the clinical phenotype of PCOS in adolescents. Subsequently...