ESPE Abstracts

Background: The increased prevalence of youth obesity has led to raised youth-onset type 2 diabetes mellitus (T2DM), as well as the intermediate condition of prediabetes. Diagnosis of prediabetes can help preventing of the development of T2DM.Aims: to study the frequency, clinical laboratory diagnostics and relationship of prediabetes with SDS BMI in obese adolescents.Materials: Th...

Background: The development of diabetes mellitus type 2 (T2DM) involves a disbalance between pancreatic β-cell function and insulin sensitivity. The impact and sequence of pathological mechanisms involved in the development of T2DM in adolescents haven’t been established.Aims: To compare the role of pancreatic β-cell dysfunction and insulin resistance in the development of prediabetes and T2DM in obese ad...