hrp0098fc2.4 | Bone, Growth Plate and Mineral Metabolism | ESPE2024

Analysis of baseline data from the SUNFLOWER longitudinal, observational cohort study of patients with XLH: relationship between various complications and QOL

Namba Noriyuki , Ito Nobuaki , Michigami Toshimi , Gyung Kang Hee , Kubota Takuo , Miyazaki Osamu , Shintani Ayumi , Kabata Daijiro , Nishida Yayoi , Fukumoto Seiji , Ozono Keiichi

X-linked hypophosphatemia (XLH) is characterized by excess FGF 23, hypophosphatemia, skeletal deformities, and growth impairment. Due to the lack of large-scale and long-term observational studies, not enough evidence has been accumulated to gain consensus on optimal care. A longitudinal, observational cohort study (SUNFLOWER) was initiated in Japan and South Korea to clarify the course of XLH; delineate its physical, mental, and financial burdens; and collect information on t...