hrp0098p3-266 | Thyroid | ESPE2024

TRAb, a nasty joke: two cases of neonatal hyperthyroidism in newborns of mothers affected by autoimmune hypothyroidism.

Teresa Petralia Ilenia , Abbate Marco , Santagiuliana Cristina , Vincenzi Gaia , Cristofori Gloria , Fumagalli Monica , Barera Graziano , Cristina Vigone Maria

We present two cases of preterm newborns affected by autoimmune hyperthyroidism: patient A, a four-day-old male, and patient B, a seven-day-old female. Patient A was born at 33+6 gestational weeks (GW) by eutocic delivery; pregnancy was complicated by maternal autoimmune hypothyroidism. The mother was diagnosed with autoimmune thyroiditis eight years earlier, with positivity for anti- thyroperoxidase antibodies (TPOAb), in the absence of TSH receptor antibodies (TRAb). After a...