hrp0097p2-56 | Bone, Growth Plate and Mineral Metabolism | ESPE2023
, Meneghin Alice
, Monti Elena
, Trevisson Eva
, Guazzarotti Laura
Pathologically elevated serum levels of fibroblast growth factor-23 (FGF23), a bone-secreted hormone that regulates phosphorus homeostasis, result in renal phosphate wasting leading to rickets or osteomalacia. Patterns leading to FGF23 excess are still unknown. Recently, FGF23 elevated rickets has been associated with epidermal nevus syndrome, designating the cutaneous skeletal hypophosphatemia syndrome (CSHS). The clinical picture is not completely defined as, to date, only a...