hrp0098rfc1.2 | Diabetes and Insulin | ESPE2024

Evaluating Glucose-6-Phosphate Dehydrogenase Enzyme Activity In Children With Type 1 Diabetes Mellitus.

Abdelmeguid Yasmine , Mosaad Nesma , Khater Doaa

Introduction: Type 1 diabetes mellitus (T1DM) remains the most common form of diabetes in young people. Little is known about the relationship between G6PD deficiency and DM. However, experimental observations support the hypothesis that hyperglycemia can lead to a decrease of G6PD activity, which is of major importance for defense against oxidative stress. Hyperglycemia may lead to the production of free radicals that are known to contribute to the pathogenes...