hrp0098p1-201 | Thyroid 2 | ESPE2024

Potential Role of Selected miRNAs in the Pathogenesis of Autoimmune Thyroid Diseases in Children and Adolescents

Sawicka Beata , Sulewska Anetta , Kulczyńska- Przybik Agnieszka , Bossowski Filip , Dulewicz Maciej , Borysewicz-Sańczyk Hanna , Mroczko Barbara , Niklinski Jacek , Bossowski Artur

Background: Many epigenetic factors, including microRNAs, are involved in the process of changing gene expression. MiRNAs are small non-coding RNA molecules that regulate gene translation by silencing or degrading target mRNAs. They are recognized as novel diagnostic and prognostic biomarkers for many diseases. Patients with autoimmune thyroid diseases are more likely to develop nodules in the thyroid tissue, and Hashimoto's thyroiditis and Graves’ ...