hrp0098p2-313 | Late Breaking | ESPE2024

Correlation of Bone Health Index (BHI) and Metacarpal Index (MCI) with calcium metabolism parameters in children and adolescents

Ntova Maria , Chrysis Dionysios , Dermitzaki Eleni , N Michoula Aspasia , Christopoulos Panayiotis , Mastorakos George , N Grivea Ioanna , T Papadimitriou Dimitrios

Introduction: The assessment of bone maturation with artificial intelligence (AI) has introduced new straightforward indicators of bone health monitoring related the much more complex and expensive method of measuring bone density with DEXA (Dual-Energy X-Ray Absorptiometry). Bone Health Index (BHI) describes bone mass as a function of cortical thickness, width and length of the three middle metacarpals, using digital hand X-rays for bone age evaluation from D...

hrp0098p2-314 | Late Breaking | ESPE2024

Bone Health Index (BHI) and Metacarpal Index (MCI) in boys and girls on treatment with aromatase inhibitors

Piperidou Alexandra , Chrysis Dionysios , Dermitzaki Eleni , N Michoula Aspasia , Christopoulos Panayiotis , Mastorakos George , N Grivea Ioanna , T Papadimitriou Dimitrios

Third generation AIs have been repurposed as an off-label treatment in boys and girls, as they can retard closure of the epiphysial plate expanding the period of growth. Assessment of digital hand X-rays has introduced new follow-up indexes of bone health: Bone Health Index (BHI) from DICOM files describes bone mass as a function of cortical thickness, and Metacarpal Index (MCI) from digitized files expresses the cortical thickness standardized for the outer bone diameter at t...

hrp0098p3-284 | Late Breaking | ESPE2024

Dramatic deterioration of subclinical hyperparathyroidism in children and adolescents during the post-COVID-19 period

Loutsou Maria , Dermitzaki Eleni , Christopoulos Panayiotis , N Michoula Aspasia , Mastorakos George , Diamantopoulos Stavros , N Grivea Ioanna , T Papadimitriou Dimitrios

Vitamin D is a steroid hormone, essential for the immune system and bone health. Given that sun exposure is meant to provide at least 80% of daily vitamin D requirements, the COVID-19 pandemic is likely to have a considerable influence on calcium metabolism We retrieved anonymized data on calcium metabolism parameters assessing the occurrence of subclinical hyperparathyroidism – subclinical nutritional rickets (PTH ≥ 45 pg/ml with normal serum Ca ≤ 10.5 mg/dl) in c...