hrp0082p3-d2-635 | Adrenals & HP Axis (1) | ESPE2014

Congenital Adrenal Hyperplasia: Survey of the Management in Children Across UK

Niranjan Usha , Natarajan Anuja

Background: The ultimate goal in the management of congenital adrenal hyperplasia (CAH) in children is to achieve normal growth and development which can be a challenge. The consensus guidance recommends hydrocortisone (10–20 mg/m2 per day) and fludrocortisone(50–200 μg/day) therapy titrated carefully with regular monitoring.Objective and hypotheses: To determine the current practise in UK regarding the management of CAH in chil...

hrp0094p2-160 | Diabetes and insulin | ESPE2021

HbA1C stability – is posting samples reliable?

Davey Nicola , Wright Katherine , Natarajan Anuja ,

For the safe delivery of Paediatric Diabetes services at DBTH during the COVID pandemic a postal HbA1c service with patients collecting capillary blood samples to send to the laboratory for analysis was proposed. The aim of this pilot study was to assess stability of HbA1c at ambient temperature in capillary whole blood samples collected into Sarstedt Microvette EDTA tubes. Samples were analysed on the day of collection on the TOSOH G11 analyser and then re-assayed daily for u...

hrp0082p3-d2-892 | Perinatal and Neonatal Endocrinology (1) | ESPE2014

Subcutaneous Fat Necrosis Causing Prolonged Hypercalcaemia in a Neonate: an Unusual Case

Niranjan Usha , Desai Vivek , Brooke Nigel , Natarajan Anuja

Introduction: Subcutaneous fat necrosis (SCFN) is an uncommon inflammatory disorder of the adipose tissue. Though hypercalcaemia secondary to SCFN is a well-recognised entity, reported cases with persistence of symptoms requiring prolonged treatment as in our case are rare. There are also limited reports about the severity and duration of hypercalcaemia secondary to SCFN with possible correlation of the severity to the extensity of the skin lesions. We present a neonate who de...

hrp0084p3-1147 | Puberty | ESPE2015

Persistent Isolated Cyclical Vaginal Bleeding (Premature Menarche) not Associated with GnRH Pubertal Response or Endometrial Echo Should be Considered for Examination Under General Anaesthesia

Upadrasta Swathi , Watson Lauren , Natarajan Anuja , Ng Sze May

Background: Isolated prepubertal menarche is described in the absence of any other signs of precocious sexual development. This condition remains unclear in its aetiology and there is currently no consensus on investigations to be undertaken.Objective and hypotheses: The objective of our study is to evaluate the following factors associated with persistent isolated cyclical vaginal bleeding: clinical presentation, gonadotrophin-releasing hormone (GnRH) s...

hrp0084p1-50 | Diabetes | ESPE2015

A Feasibility Study of Intra-Gastric Balloons (Supported By a Lifestyle Programme) for the Treatment of Severe Adolescent Obesity: the (Bob) Study

Sachdev Pooja , Reece Lindesy , Copeland Rob , Thomson Mike , Natarajan Anuja , Wales Jerry , Wright Neil

Rationale: Although many adolescents meet the NICE criteria for bariatric surgery in the UK, there is a reluctance to undertake or commission irreversible procedures in young people. Balloons are temporary, reversible, safer and in adults have been shown to promote a clinically significant change in BMI of between 4.0 and 9.0 kg/m2. However due to subsequent weight regain, bypass surgery is preferred in adults. In adolescents, more amenable to change, balloons may p...