ESPE Abstracts

Background: Multiple causes of hyperprolactinemia can be identified in some patients with rheumatic diseases. Prolactin maintains cartilage maintenance, osteogenesis, growth, proliferation and apoptosis as well as the release of proinflammatory mediators by immune cells – events that can both induce and prevent rheumatic diseases. The aim of this study is to analyze the serum prolactin level in patients with juvenile idiopathic arthritis (JIA), and their ...

Background: Glucocorticoid (GC) treatment is associated with many unwanted effects but osteoporosis and fractures are the most serious adverse events. Several large case–control studies have shown strong associations between exposure to glucocorticoids and the risk of fractures. By other hand, multiple factors have been associated with avascular necrosis (AVN) in systemic lupus erythematosus (SLE), but it is steroid use that has been...

Background: In children, severe obesity represents a growing public health concern, with implications for both immediate and long-term health outcomes. We present a complex case of an 8-year-old female with autism spectrum disorder (ASD), systemic sclerosis, and severe obesity, further complicated by insulin resistance and poor metabolic control.Case Presentation: Laboratory findings indicate liver inflammation or damage...

Background: Autoimmune thyroiditis, which can occur in chronic arthritis, involves the immune system attacking the thyroid gland, potentially causing hypothyroidism or hyperthyroidism. However, data on thyroid involvement in Still's disease remains limited, highlighting a significant gap in understanding the full spectrum of autoimmune and autoinflammatory interactions in this condition.The study aims: to examine th...