hrp0092p3-300 | Late Breaking Abstracts | ESPE2019

Height and Upper/Lower Body Ratio in Turner Syndrome Adolescents in Indonesia; Is There any Significant Difference Based on Karyotype?

Novina Novina , Gunardi Hartono , Pulungan Aman B.

2Department of Pediatrics, Faculty of Medicine, University of Indonesia, Jakarta, IndonesiaBackground: Short stature is one of the most common findings in Turner syndrome. There are two types of Turner syndrome based on karyotype: classical and mosaic. It is often marked by the body disproportion and dysmorphic profile of the patients. There are still not many data available regarding upper lower body segment ratio (U/L body s...

hrp0095p2-35 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Parathyroid Hormone and Its Relationship to Calcium, Magnesium, and Phosphate in Children age 2 – 5 years old with Abnormal Levels of Vitamin D

Novina Novina , Bhakti Pulungan Aman , Dias Ismiarto Yoyos , Setiabudiawan Budi

Background: Parathyroid Hormone (PTH), a key regulator of calcium and phosphorus homeostasis through its effect on bone, kidney, and intestine. The serum concentration of PTH is derived both from the release of PTH stored in secretory granules and from de novo synthesis of PTH in response to alterations in the serum levels of calcium, phosphorus, and vitamin D. Magnesium has a potent role in secretion of PTH, while alkaline phosphatase appears to be important ...

hrp0095p2-9 | Adrenals and HPA Axis | ESPE2022

Thrombocytosis as a Rare Manifestation in Salt Wasting Congenital Adrenal Hyperplasia: A Case Report

Novina Novina , Aprimadhansari Aprimadhansari , Nurfandi Wendi , Sunhaya Ratna , Saraswati Citra , Oktavianus Trisaputra Jessica

Introduction: Congenital adrenal hyperplasia (CAH) has an incidence of 1:14 000 to 1:18 000 worldwide. It is caused by autosomal recessive gene mutations. Neonates typically present with virilization at birth, or in shock, ‘salt-losing crisis’, around days 10–14 of life. Some children present later with simple virilizing CAH, often with milder compound heterozygous mutations. Reactive thrombocytosis is a rare manifestation in CAH. Gasparini <...

hrp0095p2-300 | Thyroid | ESPE2022

Thyroid Function and Congenital Heart Defects in Children with Down Syndrome at Hasan Sadikin General Hospital, Bandung, Indonesia

Andriyani Dwi , Novina Novina , Rayani Apandi Putria , Faisal Faisal , Budi Kuswiyanto Rahmat , Endah Rahayuningsih Sri

Introduction: Down Syndrome (DS) is a genetic disorder that has a high mortality rate and a large number of comorbidities such as hypothyroidism and heart disease. Thyroid hormones have significant effects on cardiovascular. This study aims to describe thyroid function and congenital heart defects in Down Syndrome children at dr. Hasan Sadikin General Hospital.Methods: This is a cross-sectional study. The inclusion crite...

hrp0095p2-38 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Is Platinum-Based Chemotherapy resulted Hypomagnesemia in a Girl with Osteosarcoma? A Case Report

Novina Novina , Aprilianti Dea , Faisal Faisal , Melani Sari Nur , Suryawan Nur , Susanah Susi , Milanti Dewi Mia , Hawani Dewi , Solek Purboyo , Amalia Risan Nelly

Introduction: Magnesium is the second most abundant intracellular cation, and its low level causes several side effects related to hypoparathyroidism, hypocalcaemia, and vitamin D deficiency. Furthermore, some of the cases of hypomagnesemia are linked to platinum-based chemotherapy, resulting in neurotoxicity and nephrotoxicity. Dorsal root ganglion is the main target of platinum drugs, whereby its signs and symptoms can be detected months after chemotherapy. ...