hrp0086p2-p330 | Diabetes P2 | ESPE2016

Lipid Metabolism in Children with Diabetes Mellitus Type 1

Latyshev Dmitri , Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Lobanov Yuri

Objective and hypotheses: To study the lipid metabolism in children with diabetes type 1.Method: It was included 44 children (33 girls), the average age – 10.2±3.3 years. Patients were divided: group 1 (less than 5 years) – 23 children (17 girls), mean age 9.8±3.6, the average length of diabetes 2.08±1.5 years. The second (over 5 years) – 21 children (16 girls), mean age of 11.6±2.4, the average length – 7.5±1...

hrp0082p3-d1-767 | Fat Metabolism & Obesity | ESPE2014

Prevalence Metabolic Syndrome and Its Components Among Children with Obesity

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov , Kolomina Irina

Background and aims: To study the prevalence of metabolic syndrome and its components (impaired fasting and after overload glucose, type 2 diabetes mellitus, low cholesterol HDL, and high triglycerides) in children with obesity.Methods: This research includes 550 (65.8% boys) children, recruited from Pediatric Endocrinology Department, with abdominal obesity. We measured BMI, waist circumference, blood pressure with standard instrumentation and glucose (...

hrp0082p3-d3-940 | Puberty and Neuroendocrinology (1) | ESPE2014

Inhibin B in the Boys with Constitutional Delay of Puberty: Relationship with Gonadotropins, Testosterone, and Anti-Müllerian Factor

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov

Objective: The aim of this study were to investigate the level of inhibin B and its relationship with testosterone, anti-Müllerian factor, basal, and GnRH-stimulated gonadotropin hormones (LH and FSH) concentration in boys with constitutional delay of puberty.Material and methods: In the study were included 15 boys (mean age 14.5±1.6 years) in Tanner stages 1–2. The investigation consists of genital examination with prader orchidometer, de...

hrp0092p1-147 | Thyroid | ESPE2019

Intrathyroidal Ectopia of Thymus in Children: Frequency, Ultrasound, Evolution

Okminyan Goar , Rogova Olga , Pykov Mihail , Lavrova Tatyana , Kiselyova Elena , Latyshev Oleg , Samsonova Lyubov

Objectives: to study the frequency, ultrasound characteristics and the evolution of intrathyroidal ectopia of thymus(IET) in children.Materials and Methods: as part of an epidemiological study (2014-2017), an assessment consists of incidence of IET in pre-puberty children, which using ultrasound of 1164 patients (604 girls, 560 boys). As part of a clinical study (2014-2019), the ultrasound characteristics and the evoluti...

hrp0092p3-224 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Clinical and Laboratory Characteristics of Different Various Types of Gonadal Dysgenesis in Girls with Hypergonadotropic Hypogonadism

Kabolova Kseniya , Oleg Latyshev , Lubov Samsonova , Elena Kiseleva , Goar Okminyan , Kristina Kokoreva , Elvira Kasatkina

Objective: to evaluate clinical and laboratory characteristics of various types of gonadal dysgenesis in girls with hypergonadotropic hypogonadism.Methods: 17 girls with hypergonadotropic hypogonadism (13.9±3.72) were examined. Inclusion criteria: characteristics of delayed puberty, no disorders of sex development, presence of müllerian duct derivatives, high levels of gonadotrophins. Tanner stage, antropometri...

hrp0092p3-242 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Clinical and Laboratory Characteristics of Patients with Different Variants of Gonadal Dysgenesis

Latyshev Oleg , Sannikova Ekaterina , Samsonova Lubov , Kiseleva Elena , Okminyan Goar , Kasatkina Elvira , Volodko Elena , Dondup Olga

Objective: To study clinical and laboratory characteristics of patients with disorders of sex development (DSD) 45,X/46,XY and 46,XY, partial gonadal dysgenesis.Subjects and Methods: It was included 27 patients with disorders of gonadal dysgenesis at birth to 9 years, which were divided into groups based on cytogenetic survey – DSD 46,XY, partial gonadal dysgenesis (n=10) and DSD 45,X/46,XY (n&...

hrp0092p3-253 | Thyroid | ESPE2019

Child Thyrotoxicosis Syndrome: Structure and Characteristics

Evsyukova Evgeniya , Kolomina Irina , Bukin Sergey , Kisileva Elena , Latyshev Oleg , Okminyan Goar , Samsonova Lyubov

Objective: To study the structure and characteristics of child thyrotoxicosis syndrome.Materials and Methods: At the 1st stage, medical records of patients treated at the Endocrinology Unit of the Children's Hospital named after Z.A. Bashlyaeva of the City of Moscow in 2014-2018 (n=4530) were analyzed. At the 2nd stage, a primary examination of 106 children 3 to 17 years old with a diagnosis of thyrotoxi...

hrp0089p3-p092 | Diabetes & Insulin P3 | ESPE2018

Predictors of Optimal Glycemic Control in Children with Diabetes Mellitus Type 1 Receiving Pump Insulin Therapy

Evsyukova Evgeniya , Kolomina Irina , Bukin Sergey , Kiseleva Elena , Latyshev Oleg , Okminyan Goar , Samsonova Lyubov

Objectives: To study predictors of target levels of glycosylated hemoglobin (HbA1c) in children with diabetes mellitus type 1 (DM1), receiving pump insulin treatment.Materials and Methods: 64 children (27 girls, 46 adolescents) with diabetes mellitus type 1 (mean age 12.8±3.5 years, disease duration 4.46±3.1 years, daily insulin dose 0.82±0.24 units) receiving pump insulin treatment for 2.46±1.43 years were studied. The res...

hrp0089p3-p117 | Diabetes & Insulin P3 | ESPE2018

Compliance for Monitoring of Glycemic Control in Children with Type 1 Diabetes

Latyshev Oleg , Simakova Maria , Samsonova Lyubov , Okminyan Goar , Kiseleva Elena , Fialtov Alexander , Kasatkina Elvira

Topic: Compliance for monitoring of glycemic control in children with type 1 diabetes.Background and Aims: To estimate attachment of children with type 1 diabetes to self-control of blood glucose with help of automatically data processing system of glycemic control.Method: We have checked 54 patients with first type diabetes at the age 14±3, 4 years old (32 males, 22 females), divided into two age groups: from 0 to 14, and 15-...

hrp0089p2-p314 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

The Start Predictors of Puberty in Boys with Constitutional Delay of Puberty

Brzhezinskaia Liubov , Samsonova Lyubov , Latyshev Oleg , Okminyan Goar , Kiseleva Elena , Kasatkina Elvira

Objective: To examine the clinical and hormonal predictors of start pubertal in boys with constitutional delay of puberty (CDP).Materials and methods: The study included 42 boys with CDP (Tanner1, max LH>10 IU/l of GnRH stimulation test). At the first visit in 14.5±0.7 years we evaluated anthropometric indicators, bone age, testicular volume and hormonal status (TSH, freeT4, prolactin, IGF-1, insulin, DHEAS, cortisol, LH, FSH, estradiol, testost...