hrp0092p3-129 | Fat, Metabolism and Obesity | ESPE2019

Influence of Anthropometric Indices at Birth on Obesity Characteristics in School-Age Children

Latyshev Dmitry , Latyshev Oleg , Lobanov Yuri , Karkova Tatyana

Influence of anthropometric indices at birth on obesity characteristics in school-age children Latyshev D. Yu., Lobanov Yu. F.? Latyshev O. Yu. *, Karkova T.A. Altai State Medical University, Barnaul * Russian Medical Academy of Postgraduate Education. Moscow Keywords: obesity, children, body length, body mass index Objective: To study the relationship between anthropometric data at birth and the course of obesity in school-age children. Materials and metho...

hrp0086p2-p330 | Diabetes P2 | ESPE2016

Lipid Metabolism in Children with Diabetes Mellitus Type 1

Latyshev Dmitri , Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Lobanov Yuri

Objective and hypotheses: To study the lipid metabolism in children with diabetes type 1.Method: It was included 44 children (33 girls), the average age – 10.2±3.3 years. Patients were divided: group 1 (less than 5 years) – 23 children (17 girls), mean age 9.8±3.6, the average length of diabetes 2.08±1.5 years. The second (over 5 years) – 21 children (16 girls), mean age of 11.6±2.4, the average length – 7.5±1...

hrp0082p3-d1-767 | Fat Metabolism & Obesity | ESPE2014

Prevalence Metabolic Syndrome and Its Components Among Children with Obesity

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov , Kolomina Irina

Background and aims: To study the prevalence of metabolic syndrome and its components (impaired fasting and after overload glucose, type 2 diabetes mellitus, low cholesterol HDL, and high triglycerides) in children with obesity.Methods: This research includes 550 (65.8% boys) children, recruited from Pediatric Endocrinology Department, with abdominal obesity. We measured BMI, waist circumference, blood pressure with standard instrumentation and glucose (...

hrp0082p3-d3-940 | Puberty and Neuroendocrinology (1) | ESPE2014

Inhibin B in the Boys with Constitutional Delay of Puberty: Relationship with Gonadotropins, Testosterone, and Anti-Müllerian Factor

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov

Objective: The aim of this study were to investigate the level of inhibin B and its relationship with testosterone, anti-Müllerian factor, basal, and GnRH-stimulated gonadotropin hormones (LH and FSH) concentration in boys with constitutional delay of puberty.Material and methods: In the study were included 15 boys (mean age 14.5±1.6 years) in Tanner stages 1–2. The investigation consists of genital examination with prader orchidometer, de...

hrp0084p3-796 | DSD | ESPE2015

Tumours of Gonads in Patients with Disorders of Sex Development – 46,XY Gonadal Dysgenesis

Latyshev Oleg , Samsonova Lubov , Okulov Alexey , Kiseleva Elena , Okmynuan Guar

Background: Disorders of sex development, especially with Y chromosome material, are the main factor of an increased risk of gonadal tumour. The main idea of this study was to investigate the prevalence of gonad tumours in patients with 46,XY gonadal dysgenesis.Methods: This study included 9 patients with 46,XY gonadal dysgenesis: seven patients with partial and two with total gonadal dysgenesis. Among nine patients there were two patients with Frasier s...

hrp0097p2-316 | Late Breaking | ESPE2023

Family case of constitutional delay of puberty

Latyshev Oleg , Okminyan Goar , Kiseleva Elena , Romaykina Daria , Samsonova Lubov

Introduction: One of the strategies of searching the genetic causes of CDGP is analysing the genes responsible for hypogonadotropic hypogonadism (HH).Objective: To investigate the role of the HS6ST1 gene in development CDGP.Materials and Methods: Two patients - height and BMI SDS, bone age, genitometric parameters, basal hormones, GnRH analogue test, hCG test, olfactometry, brain-M...

hrp0095p1-37 | Diabetes and Insulin | ESPE2022

The role of insulin resistance and pancreatic β-cell dysfunction in the development of prediabetes in obese adolescents

MinkovaNadezda , Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Romaykina Daria , Samsonova Lubov

Background: The pathophysiology of type 2 diabetes mellitus (T2DM) is based on defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. Young people have a more aggressive course of the disease. However, the impact and sequence of pathological mechanisms involved in the development of T2DM in adolescents hasn’t been established. Diagnosis of the prediabetes in time can be u...

hrp0095p2-112 | Fat, Metabolism and Obesity | ESPE2022

Prediabetes in Obesity Adolescents: Frequency, Structure, Relationship with Body Mass Index

Minkova Nadezda , Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Romaykina Daria , Samsonova Lubov

Background: The increased prevalence of youth obesity has led to raised youth-onset type 2 diabetes mellitus (T2DM), as well as the intermediate condition of prediabetes. Diagnosis of prediabetes can help preventing of the development of T2DM.Aims: to study the frequency, clinical laboratory diagnostics and relationship of prediabetes with SDS BMI in obese adolescents.Materials: Th...

hrp0095p2-258 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Comparative characterization of hypogonadotropic hypogonadism and constitutional delayed puberty in girls

Kabolova Kseniya , Latyshev Oleg , Samsonova Lubov , Romaykina Daria , Okminyan Goar , Kiseleva Elena

Objective of the research: To compare clinical laboratory and genitometric parameters in girls with hypogonadotropic hypogonadism (HH) and constitutional delayed puberty (CDP).Materials and Methods: 23 female patients with delayed puberty are included in the study.Inclusion criteria: Absence of secondary sexual characteristics at age ≥13 years or absence of menarche at age ≥1...

hrp0092p1-147 | Thyroid | ESPE2019

Intrathyroidal Ectopia of Thymus in Children: Frequency, Ultrasound, Evolution

Okminyan Goar , Rogova Olga , Pykov Mihail , Lavrova Tatyana , Kiselyova Elena , Latyshev Oleg , Samsonova Lyubov

Objectives: to study the frequency, ultrasound characteristics and the evolution of intrathyroidal ectopia of thymus(IET) in children.Materials and Methods: as part of an epidemiological study (2014-2017), an assessment consists of incidence of IET in pre-puberty children, which using ultrasound of 1164 patients (604 girls, 560 boys). As part of a clinical study (2014-2019), the ultrasound characteristics and the evoluti...