hrp0084fc7.4 | Growth-promoting therapies | ESPE2015
Zuckerman-Levin Nehama
, Gucev Zoran
, de Schepper Jean
, Rasmussen Michael Hojby
, Battelino Tadej
, Olsen Minna Braendholt
, Savendahl Lars
Background: GH administration restores normal growth in children with GH deficiency (GHD). However, current daily s.c. injection treatment regimens may be inconvenient leading to impaired adherence and subsequently suboptimal treatment outcomes. NNC0195-0092 is a novel, reversible albumin-binding GH developed for once-weekly administration.Objective and hypotheses: This was a randomised, open-label, active-controlled, dose-escalation trial (NCT01973244) ...