hrp0086p2-p713 | Endocrinology and Multisystemic Diseases P2 | ESPE2016
, Majıdov Ilkın
, Ozen Samim
, Onay Husein
, Darcan Sukran
Background: Wolfram syndrome is an autosomal recessive disorder accompanied by diabetes insipidus, diabetes mellitus, optic atrophy and deafness. Mutations in the WFS1 gene are determined in 90% of cases. We present the clinical features of three cases of Wolfram syndrome.Objective and hypotheses: Case 1: A 14-year-old girl presented with loss of vision. At the age of 3 years she had been diagnosed with type 1 diabetes mellitus with a bl...