hrp0084p3-1008 | Growth | ESPE2015

Presenting Characteristics, Auxological, and Aetiologic Evaluation of 364 Patients with GH Deficiency

Ozbek Mehmet Nuri , Baysal Birsen , Tanriverdi Sibel , Deniz Ahmet , Oncel Kahraman , Ocal Murat , Baran Riza Taner , Demirbilek Huseyin

Background: GH deficiency (GHD), can either be isolated (IGHD) or part of multiple pituitary hormone deficiency (MPHD), is a pituitary hormone disorder that manifests with short stature.Objective and hypotheses: To evaluate the presenting characteristics, auxological and etiologic factors of GHD in a large cohort from a single tertiary paediatric endocrine centre.Methods: Hospital files of patients followed with GHD deficiency at D...

hrp0084p3-1229 | Thyroid | ESPE2015

Euthyroid Sick Syndrome in Children Presenting with Diabetic Ketoacidosis

Baran Riza Taner , Demirbilek Huseyin , Dundar Munevver , Aydin Mulkiye , Demir Remezan , Karatas Mustafa , Tas Funda , Oncel Kahraman , Ozbek Mehmet Nuri

Background: Euthyroid sick syndrome (ESS), also known as non-thyroidal illness or low T3 syndrome, is defined as low T3, low/normal T4 and inability of rise in TSH due to extrathyroidal diseases. Any condition resulting stress such as infectious diseases, sepsis, metabolic disorders and severe malnutrition can associate to ESS. Patients presented with type 1 diabetes mellitus (T1DM) are usually being screened for other autoimmune diseases inclu...

hrp0084p3-1078 | Hypo | ESPE2015

Long Acting Somatostatin Analogues in the Management of Congenital Hyperinsulinism in Cases with Poor Compliance to Conventional Therapy

Demirbilek Huseyin , Oncel Kahraman , Ozbek Mehmet Nuri , Deniz Ahmet , Baysal Birsen , Arya Ved Bhushan , Flanagan Sarah E , Ellard Sian , Hussain Khalid

Background: Congenital hyperinsulinism (CHI), is the most common cause of severe hypoglycaemia in neonates and infants. The cornerstone of medical therapy is diazoxide. Octreotide, a somatostatin analogue, is the second therapeutic option in diazoxide unresponsive cases. However, due to its short half-life and requirement of multiple daily doses, lack of compliance may cause recurring hypoglycaemia and related neurological deficits, particularly for the family with low socioec...