ESPE Abstracts

Recent studies demonstrate the pivotal roles that bone-making somatic stem cells – skeletal stem cells – play in skeletal development and growth. Subtle alterations in the skeletal stem cell compartment introduced genetically or epigenetically could amplify within their derivatives, resulting in aberrations of skeletal structures and functions. The emerging concept is that skeletal stem cells are not a monolithic group of cells with homogeneous identities. Instead,...