hrp0097p1-211 | Adrenals and HPA Axis | ESPE2023
Park Julie
, Hawcutt Daniel
, Shantsila Alena
, Bright Orla
, Dliso Silothabo
, Lip Gregory
, Blair Joanne
Background: 11-oxygenated 19-carbon (11oxC19) steroids, 11ketotestosterone (11KT) and 11βhydroxyandrostenedione(11OHA4) are adrenally derived steroids that rise in congenital adrenal hyperplasia (CAH). Increased 11oxC19 concentrations are associated with markers of poor control of CAH. To date, 11oxC19 concentrations have not been measured in patients with Addison’s disease (AD).Methods: Children with primary ...