hrp0089p1-p130 | Fat, Metabolism and Obesity P1 | ESPE2018

The Frequency of Obstructive Sleep Apnea in Children with Hypothalamic and Exogenous Obesity

Iyigun Irem , Alikasifoglu Ayfer , Ozon Alev , Gonc Nazli , Hizal Mina , Eryilmaz Sanem , Kiper Nural , Ozcelik Ugur

Introduction: Hypothalamus is an important regulator of sleep onset, sleep maintenance and wakefulness as well as appetite control. Thus, hypothalamic damage can lead to both sleep dysregulation and severe morbid obesity. So, sleep apnea may be more prevalent and severe in obesity due to hypothalamic damage in comparison to exogenous obesity.Aim: We aim to compare frequency and severity of obstructive sleep apnea (OSA) in children with hypothalamic and e...

hrp0097p1-35 | Diabetes and Insulin | ESPE2023

Effects of insulin therapy on respiratory functions, pulmonary exacerbation and nutritional status in cystic fibrosis-related diabetes

Vuralli Dogus , Alboga Didem , Senkalfa Burcu , Gozmen Onur , Yalcin Ebru , Dogru Ersoz Deniz , Ozcelik Ugur , Kiper Nural , Gonc Nazli , Ozon Alev

Background and Aim: Cystic fibrosis-related diabetes (CFRD) is a common extrapulmonary comorbidity in patients with cystic fibrosis (CF). Since CFRD is clinically silent in the early period, it is recommended to evaluate glucose metabolism with an oral glucose tolerance test (OGTT) annually in CF patients aged 10 years and older. Insulin therapy is thought to improve lung function and nutritional status in patients with CFRD. In this study, we aimed to evaluat...