hrp0084p2-576 | Thyroid | ESPE2015

Relationship between Cord Blood Phthalates and Maternal and Neonatal Thyroid Functions

Ozsoylu Serkan , Akin Leyla , Gunes Tamer , Kendirci Mustafa , Narin Figen , Kurtoglu Selim

Background: Phthalates are industrial chemicals extensively used as plasticizers in a variety of commercial products. Di-(2-ethylhexyl) phthalate (DEHP) is one of the most frequently used phthalates. DEHP is readily metabolized to mono-(2-ethylhexyl) phthalate (MEHP), which is more toxic than its parent compound. There are some animal and in vitro studies suggesting that phthalates can disrupt hypothalamus-pituitary-thyroid axis.Objective and hy...