ESPE Abstracts

Background: Previous research demonstrated that survivors of childhood acute lymphoblastic leukemia (ALL), treated on the Italian Association of Pediatric Hematology and Oncology (AIEOP) protocols without radiotherapy between 1989 and 2000, generally achieve a normal final height with a body mass index (BMI) within the normal range. Nevertheless, their height catch-up growth is not fully restored after chemotherapy and BMI increases during treatment. In female...

Background: Children with Sickle Cell Disease (SCD) show endocrine complications and metabolic alterations. The physiopathology of these conditions is not completely understood: iron overload due to chronic transfusions, ischemic damage, and inflammatory state related to vaso-occlusive crises may be involved. Aims of this study were to evaluate the growth pattern and the endocrine and metabolic alterations in a cohort of children with SCD and to detect the relationship between...