hrp0086rfc1.1 | Adrenals | ESPE2016
, Nicolaides Nicolas C.
, Papageorgiou Louis
, Lamprokostopoulou Agaristi
, Charmandari Evangelia
Background: The nuclear receptor (NR) family comprises three main subfamilies: the steroid hormones receptors, the thyroid/retinoid hormone receptors and the orphan receptors. Proteins within the NR family share common domain architecture. These closely related receptors and their cognate ligand compounds play a key role in homeostasis, reproduction, growth and development. Despite their biological significance, their evolution and diversification remains to be elucidated....