hrp0098fc1.2 | Diabetes and Insulin | ESPE2024

Effect of hydroxychloroquine therapy in newly diagnosed type 1 diabetes: a randomised, double-blind, placebo-control pilot trial

George Arun , Kumar Rakesh , Patil Amol , Sachdeva Naresh , Yadav Jaivinder , Jacob Neenu , Banerjee Sayan , Nanda Pamali , Bala Anju

Background: Hydroxychloroquine sulfate (HCQS) is an immunomodulatory drug used to treat various rheumatological conditions. However, its effect on preserving β-cell function in type 1 diabetes remains unclear.Objective: To determine the differences in C-peptide (fasting and post mixed meal) and HbA1c in children with new-onset T1D on hydroxychloroquine therapy versus placebo.Methods:</...