ESPE Abstracts

Introduction: Disorders of sexual development (DSD) encompass a complex group of conditions characterized by a discrepancy between phenotypic and chromosomal sex, sometimes associated with impaired sex steroid synthesis or hormone action. DSD can be detected prenatally; however, establishing their etiology remains challenging. Our objective is to identify steroid profiles that could guide prenatal molecular analyses for diagnosis and perinatal care.<p clas...

Background and Aims: Central Precocious Puberty (CPP) caused by the early activation of the hypothalamic-pituitary-gonadal axis is a rare affection that occurs in 0.2% in girls. Clinical signs are suggestive and LHRH-test could be sometimes difficult to use and not always contributive. Gonadotropin assay in twenty-four hours-urinary collection could be an interesting option. The present work intended to evaluate the diagnostic interest of 24-hour urinary gonad...