hrp0098p1-68 | Growth and Syndromes 1 | ESPE2024

Impact of Idiopathic Short Stature (ISS) on children’s well-being.

Juul Anders , Linglart Agnes , Højby Rasmussen Michael , Lund Leunbach Tina , Pietropoli Alberto , Pedersen Mikkel , de Fries Jensen Lasse

Introduction: Idiopathic short stature (ISS) is characterized by a reduced height (at least 2 standard deviation scores [SDS]) from expected norms based on age, sex, and population-specific height standards in the absence of growth hormone (GH) deficiency or other known etiologies. ISS is a registered indication for GH therapy in USA but not in Europe. The psychosocial burden of ISS remains underexplored, including its impact on quality of life. Using National...