hrp0095p1-453 | Diabetes and Insulin | ESPE2022

Usability of CGM for hyperglycemia detection during systemic glucoriticoid treatment.

Lukka Mari , Tillmann Vallo , Peet Aleksandr

Glucocorticoids are widely used to treat autoimmune and inflammatory diseases. The side-effects of glucocorticoids are well known, but not routinely monitored in the pediatric population. Recommendations regarding the timing of blood glucose screening are lacking and understanding about the correlation between different glucocorticoid treatment regimens and glucose variability is insufficient. Our objective was to test the usability of continuous glucose monitooring (CGM) to d...

hrp0092p1-289 | Thyroid (1) | ESPE2019

Thyroid Peroxidase Antibodies in Children with HLA-Conferred Susceptibility to Type 1 Diabetes

Saare Liisa , Peet Aleksandr , Tillmann Vallo

Introduction: The prevalence of thyroid peroxidase antibody (anti-TPO) positivity is estimated to be around 3-4% in healthy children and is remarkably higher in children with type 1 diabetes (T1D). However, anti-TPO positivity in children with HLA-conferred susceptibility to T1D who are not yet diagnosed with T1D, is not well studied. The aim of this study was to describe the prevalence of positive anti-TPO and its effect of thyroid function in children wi...

hrp0089p2-p378 | Thyroid P2 | ESPE2018

The Prevalence of Clinically Significant Anti-TPO Positivity in Children with HLA-Conferred Susceptibility to Type 1 Diabetes

Saare Liisa , Peet Aleksandr , Tillmann Vallo

Background: The increased prevalence of anti-thyroid peroxidase antibodies (anti-TPO) and autoimmune thyroiditis in children with type 1 diabetes (T1D) has been previously well described. However, the necessity for screening for anti-TPO in children who have not been diagnosed with T1D yet, but have a HLA-conferred susceptibility to T1D, has not been reported. A 3% prevalence of anti-TPO in healthy children has been shown in studies using a cut-off value of >100 kU/L for c...

hrp0082p2-d2-600 | Thyroid (1) | ESPE2014

Low Serum Free T4 Concentration in a Girl with McCune-Albright Syndrome

Peet Aleksandr , Roosimaa Mart , Pajuvali Anett , Tillmann Vallo

Background: McCune–Albright syndrome (MAS) is a rare disease with a prevalence of <1 to 100 000. It is caused by early post-zygotic mutations in the GNAS1 gene. Classically it presents with precocious puberty, fibrous dysplasia and café-au-lait spots. Other endocrinopathies may be hyperthyroidism, GH excess, Cushing syndrome, and renal phosphate wasting.Case report: A 17-year-old girl diagnosed with MAS at the age of 11 on basis of all thre...

hrp0094fc7.3 | Fetal Endocrinology and Multisystem Disorders | ESPE2021

European Training Requirements for Competency in Paediatric Endocrinology and Diabetes 2021

Busiah Kanetee , Peet Aleksandr , Tornese Gianluca , Weintrob Naomi , Patel Leena , Hamza Rasha ,

Background: A Europe-wide training program in Paediatric Endocrinology and Diabetes (PED) was initiated by Professor Leo Van den Brande in 1976. PED was recognised as a subspecialty in 1996 by the European Board of Paediatrics (EBP), which is a section of the Union of European Medical Specialists (UEMS). UEMS aims to ensure high standards for training across Europe and the minimum requirements are set out in the European Training Requirements (ETR). The first ...