hrp0084p2-183 | Adrenals | ESPE2015

24-H Urinary Free Cortisol as a Screening Test for Cushing’s Syndrome in Children

Shapiro Lucy , Elahi Shezan , Baliey Joe , Perry Les , Martin Lee , Grossman Ashley , Akker Scott , Monson John , Drake William , Savage Martin , Storr Helen

Background: CushingÂ’s syndrome (CS) in children remains a challenge to diagnose and exclude. Published diagnostic guidelines for CS are heavily based upon adult data. The use of 24-h urinary free cortisol (UFC) measurements in the diagnosis of adult CS may have limited use. There is little data on the utility of 24-h UFC in children.Objective and hypotheses: We hypothesised that 24-h UFC is a robust and reliable screening test in children. The study...