ESPE Abstracts

Background: Body fat distribution is associated with obesity-related disorders. Promoting subcutaneous fat proliferative expansion can reduce visceral fat ectopic deposition and the risk of obesity-related insulin resistance, hepatic steatosis, and cardiometabolic diseases. Argonaute 2 (Ago2) was found to mediate RNA silencing in the liver to regulate obesity-related energy metabolism, while its role in fat adipose tissue storing excess energy has not been add...