ESPE Abstracts

Monogenic obesity is a rare yet clinically significant condition characterized by excessive weight gain stemming from genetic mutations affecting appetite regulation and energy balance. Here, this case series explores the clinical presentation and genetic underpinnings of monogenic obesity in a familial cluster, shedding light on Laurence-Moon-Bardet-Biedl Syndrome (LMBBS) & letin deficiency associated with the genetic variants in the BBS1 and LEPR genes. The index patient...