ESPE Abstracts

Introduction: Alkaline Phosphatase (ALP) is an enzyme produced mainly by the liver and bones. Several conditions such as vitamin deficiencies or hypothyroidism can impair ALP synthesis and lead to low serum levels. Low levels can also be caused by rarer conditions such as hypophosphatasia. We noticed low levels of ALP in several of our patients with Duchenne Muscular Dystrophy (DMD) and wondered if this could be caused by low bone turnover due to high dose ste...

Introduction: The prevalence of paediatric Type 2 diabetes (T2DM) is increasing, contributed by rising incidence of obesity worldwide. Paediatric T2DM is a progressive disease with increased risk of complications and morbidities. Despite recent research, many aspects such as its pathophysiology and optimal management remain unknown.Aim: To characterise the cohort of T2DM patients across 2 large tertiary paediatric diabet...