ESPE Abstracts

ESPE Abstracts

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hrp0092fc7.2 | Diabetes and Insulin Session 2 | ESPE2019

Copeptin Kinetics and its Relationship to Osmolality During Rehydration for Diabetic Ketoacidosis in Children: An Observational Study

Burckhardt Marie-Anne , Beglinger Svetlana , Gotta Verena , Renggli Luzia , Bachmann Sara , Hess Melanie , Rentsch Katharina , Koch Gilbert , Zumsteg Urs , Jones Timothy , Pfister Marc , Szinnai Gabor

Background: Copeptin is a surrogate marker for arginine vasopressin (AVP) release in response to hyperosmolal stimuli such as diabetic ketoacidosis (DKA). We aimed to characterize the temporal course (kinetics) of serum osmolality and copeptin during rehydration and insulin therapy in children with type 1 diabetes (T1D) and DKA, and the relationship between both (dynamics).Methods: An observational multi-center study was...
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ESPE Abstracts

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