hrp0089p2-p055 | Bone, Growth Plate & Mineral Metabolism P2 | ESPE2018

Oxandrolone Improves the Linear Growth and Osteoporosis in Teenage Bays with Osteogenesis Imperfecta

Salehpour Shadab , Setavand Somayeh , Shiari Reza , Reza Yassaee Vahid , Vafadar Mehdi , Tavakoli Saeed

Background: Severe osteogenesis imperfecta (OI) is a disorder characterized by osteoporosis, frequent fractures, progressive deformity and short stature. We determine the effect of oxandrolone on predicted adult height (PAH), fracture incidence and bone mineral density in teenage boys with OI.Methods: In a prospective, double-blind, randomized, placebo-controlled clinical trial, 31 boys (12.1–16.6 years old) who were genetically proved to have OI wi...