ESPE Abstracts

Background: There are published recommendations for neonates to avoid exposure to iodine. Iodine is trapped by the thyroid gland from the blood stream and used for the synthesis of thyroid hormones. Any excess is excreted almost entirely in the urine. Acute kidney injury, especially anuria places infants at risk of toxicity when exposed to iodine and paradoxical hypothyroidism can occur (Wolff–Chaikoff effect). Hypothyroidism of sufficient severity to seriously put the br...

Background: Phaeochromocytoma is a rare neuroendocrine tumour originating from chromaffin cells in the adrenal medulla and less commonly from extra-adrenal paraganglia. Phaeochromocytoma occur in the context of a genetic syndrome in approximately 50% of adults and 80% of children. Genetic testing of index cases enables testing of first-degree relatives, identification of children who inherit the gene change and surveillance, early diagnosis and treatment of as...