hrp0097p2-271 | Late Breaking | ESPE2023

Craniosynostosis in Patients With X-Linked Hypophosphatemia: a monocentric experience

Grandone Anna , Luongo Caterina , Aiello Francesca , Romano Francesca , Miraglia Del Giudice Emanuele , Aliberti Ferdinando

Introduction: X-linked hypophosphatemic rickets (XLHR) represents the most common form of genetic hypophosphatemia and causes rickets in children because of increased FGF23 secretion and renal phosphate wasting. Even though cranial vault an craniovertebral anomalies of potential neurosurgical interest, namely early closure of the cranial sutures and Chiari type I malformation (CM-I), have been observed in children with XLH, their actual incidence and character...