ESPE Abstracts

Introduction: Thyroid hormones (THs) play a crucial role in growth, brain development and function and metabolic homeostasis. The sensitivity to TH indices seems to be associated with metabolic syndrome (MS), prediabetes and diabetes in adults. We evaluated the sensitivity to TH indices in a pediatric population with neuromotor disability in relationship with the MS presence, using a multivariate analysis (MVA).Patients and Metho...

Objectives: Increased central and peripheral sensitivity to thyroid hormones seems to be associated with an increased risk of developing prediabetes in adulthood. The objective of this study was to evaluate the relationship between the severity of obesity, the presence of glyco-metabolic alterations, and tissue sensitivity to thyroid hormones in prepubertal euthyroid children with simple obesity.Methods: Eighty prepubert...

Introduction: Both the detrimental effects on health produced by obesity, and the burden provoked on healthcare systems clearly dictate the need to provide nutritional interventions for preventing and managing obesity during childhood. Furthermore, the lifestyle habits developed in early childhood have a long lasting effect on cardiovascular and metabolic health, highlighting the importance of prevention. PODiaCar project is dedicated to enhancing the efforts ...

Aim: To evaluate whether a straightforward assessment like the Six-Minute Walking Test (6MWT) can effectively gauge the impact of an online supervised training program on lipid and glucose metabolism in a cohort of children with obesity, given the efficacy of exercise-based interventions in influencing the pathogenic processes underlying obesity-related complications.Methods: A group of 35 Caucasian children aged 8-13 wi...