hrp0089p3-p252 | Growth & Syndromes P3 | ESPE2018

Factors Influencing the Selection of Injection Areas During Self-therapy for Growth Hormone Therapy Among Patients 10–15 Years Old

Diamant Rotem

Factors Influencing the Selection of Injection Areas during Self-Therapy for Growth Hormone Therapy among Patients 10–15 Years old.Background: It is known that consistency in growth hormone therapy has major influence on long term linear growth. Many studies have researched the connections between varied growth hormone preparations, ease of use and adherence to treatment. No research was found on preference of specific injection areas and reasons fo...

hrp0094p1-171 | Growth Hormone and IGFs B | ESPE2021

Diagnosing growth hormone deficiency - Can a combined arginine and clonidine stimulation test replace two separate tests?

Oron Tal , Krieger Avihu , Yakobovich-Gavan Michal , Tenenbaum Ariel , Diamant Rotem , Phillip Moshe , Lazar Liora ,

Objective: Given a large number of false-positive growth hormone deficiency (GHD) diagnoses from a single GH stimulation test in normal children, two different pharmacological tests, performed on separate days or sequentially, are required. This study aims to assess the reliability and safety of a combined clonidine-arginine stimulation test (CACST).Design: Retrospective, single-center, observational study....

hrp0098p1-110 | Adrenals and HPA Axis 2 | ESPE2024

Does timing of Adrenocorticotropic hormone stimulation test matter?

Gil Margolis Merav , Diamant Rotem , Yackobovitch-Gavan Michal , de Vries Liat

Introduction: The ACTH stimulation test is utilized to assess cortisol reserve and when non-classical congenital adrenal hyperplasia is suspected. Limited and conflicting data exist on the impact of the time of the day on cortisol response.Aim: To study the association between peak cortisol response to ACTH test and time of the day it was conducted and to study the clinical parameters affecting this response.<p class...