hrp0092p1-341 | Fat, Metabolism and Obesity (2) | ESPE2019

ANGPTL2 and ANGPTL3 in Children with Obesity and Metabolic Syndrome

Azar Maryam Razzaghy , Nourbakhsh Mitra , Sadeghabadi Zahra Arab , Nourbakhsh Mona

Introduction: Angiopoietin-like proteins (ANGPTLs) play critical roles in metabolism and are implicated in metabolic consequences of obesity. ANGPTL2 is a key adipocyte-derived inflammatory mediator that links obesity to systemic insulin resistance. ANGPTL3 directly regulate lipid, glucose and energy metabolism independent of angiogenic effects. In this study, we aimed to investigate the levels of ANGPTL2 and 3 in obese children and adolescents and their assoc...