hrp0082fc4.6 | Growth | ESPE2014

Longitudinal Growth of Finnish Children With Gestational Diabetes in Mothers

Hakanen Tiina , Vuorela Nina , Lipiainen Ludmila , Salo Matti K , Nummi Tapio , Saha Marja-Terttu

Background: With the increase of overweight prevalence an increasing number of women develop gestational diabetes.Objective and hypotheses: We evaluated the growth of 6902 children of mothers with gestational diabetes. The secular trends in the prevalence of children with gestational diabetes in mothers was studied during 30 years.The material consisted of children born 1974 (n=1108), 1981 (n=977), 1991 (n</em...

hrp0084p2-419 | GH &amp; IGF | ESPE2015

Safety Evaluation of Long-Term Recombinant GH Treatment in Childhood: Interim Analysis of the NordiNet® International Outcome Study (IOS)

Savendahl Lars , Pournara Effie , Rohrer Tilman R , Pedersen Birgitte Tonnes , Saha Marja-Terttu , Blankenstein Oliver

Background: Long-term safety data are reported for paediatric patients treated with recombinant GH (GH; Norditropin®, Novo Nordisk A/S) at the treating physician’s discretion and enrolled in the observational NordiNet® International Outcome Study (IOS) (NCT00960128).Objective and hypotheses: To evaluate incidence rates (IR) (events/1 000 patient-years) of adverse drug reactions (ADR), serious adverse events (SAE), and...