hrp0084fc14.5 | Puberty | ESPE2015

Polybrominated Diphenyl Ethers (PBDEs) and Timing of Puberty in Girls

Deodati Annalisa , Sallemi Alessia , Maranghi Francesca , Busani Luca , Cambiaso Paola , Mancini Francesca , Scire Giuseppe , Spadoni Gian Luigi , Marini Romana , Baldari Francesca , Tassinari Roberta , Cianfarani Stefano

Background: Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants and have shown endocrine disruption properties in experimental studies. Preliminary studies in animal models have suggested a link between exposure to PBDE and alterations of puberty and reproduction.Objective and hypotheses: To investigate the association between the exposure to PBDEs and alterations of puberty in girls, referred for idiopathic premature thelarche (IP...

hrp0094p1-197 | Thyroid B | ESPE2021

Management of newborns born to mothers with autoimmune hypothyroidism

Cavarzere Paolo , Palma Laura , Camilot Marta , Vincenzi Monica , Teofoli Francesca , Principe Lara Nicolussi , Gaudino Rossella , Murri Virginia , Pepaj Orsiol , Lubrano Luigi , Rossi Giuliana , Sallemi Alessia , Fattori Ermanna , Lauriola Silvana , Antoniazzi Franco ,

Background: Maternal autoimmune hypothyroidism can have negative consequences on the fetus: on the one hand, maternal hypothyrosinemia might affect the fetal brain development in the early stages of pregnancy; on the other, thyroid inhibiting antibodies can pass through the placenta. It is currently unclear if these antibodies may affect the newbornÂ’s thyroid function. Consequently, there are no certain indications regarding the management of newborns bor...