hrp0084p3-1181 | Thyroid | ESPE2015

Early Discrimination between Transient and Permanent Congenital Hypothyroidism in Children with Eutopic Gland

Messina Maria Francesca , Aversa Tommaso , Salzano Giuseppina , Zirilli Giuseppina , Sferlazzas Concetta , De Luca Filippo , Lombardo Fortunato

Background: Congenital hypothyroidism (CH) is a common condition that occurs in ~1:3000–4000 live births and is one of the most common preventable cause of mental retardation with an early diagnosis and prompt pharmacological treatment. Neonatal screening has abolished this disease but 10% of children originally diagnosed with CH will have a transient form of the disorder and this percentage is increased during the last years due to a lowering of cut-off.<p class="abs...

hrp0084p1-32 | Diabetes | ESPE2015

Aetiological Diagnosis of Diabetes in Italian Diabetic Children and Adolescents

Delvecchio Maurizio , Salzano Giuseppina , Mozzillo Enza , Frontino Giulio , Patera Ippolita Patrizia , Toni Sonia , Rabbone Ivana , Cherubini Valentino , Tumini Stefano , D'Annunzio Giuseppe , Iughetti Lorenzo , Maltoni Giulio , Cauvin Vittoria , Marigliano Marco , Barbetti Fabrizio

Background: Type 1 diabetes (T1D) is the most frequent etiology in Italian diabetic children and adolescents. Data on type 2 (T2D) and monogenic diabetes (MD) prevalence are scanty.Objective and hypotheses: To estimate the prevalence of T1D, T2D, secondary diabetes, and MD in a pediatric population of Italian diabetic patients.Method: Data on 3,076 patients (diabetes onset January 2007–December 2012, age at diagnosis <18 y...