hrp0097p2-147 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Posterior Sellar Spine - an unusual cause of precocious puberty

Samad Punekar Abdul , Shehab Mostafa , Ehtisham Sarah

A 7 year old girl presented with breast development, mood changes and rapid growth spurt from 6.5 years. Clinically she was tall for her family and had Tanner stage 2 breast development and pubic hair. Bone age was 3 years advanced and pelvic ultrasound demonstrated globular anteverted uterus with endometrial lining and enlargement of the ovaries with follicles. LHRH test confirmed central precocious puberty with peak LH 44mIU/ml and FSH 19mIU/ml, with baseline estradiol of 92...